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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHX
All Species:
6.67
Human Site:
S36
Identified Species:
10.48
UniProt:
O00330
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00330
NP_001128496.1
501
54122
S36
V
K
G
A
L
G
W
S
V
S
R
G
A
N
W
Chimpanzee
Pan troglodytes
XP_001149489
501
54051
S36
V
K
G
A
L
G
W
S
V
S
R
G
A
N
W
Rhesus Macaque
Macaca mulatta
XP_001109997
446
48686
P21
L
R
Y
L
V
G
F
P
G
C
R
S
I
G
L
Dog
Lupus familis
XP_533153
501
54075
P36
A
R
G
A
S
G
W
P
L
G
R
G
A
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKZ9
501
53981
P36
A
Q
G
A
A
A
W
P
V
D
R
G
A
S
W
Rat
Rattus norvegicus
P08461
632
67147
G45
G
S
G
I
P
S
Y
G
V
R
S
L
C
G
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026358
502
53201
W36
A
V
P
A
R
G
G
W
R
F
L
H
G
T
Q
Frog
Xenopus laevis
NP_001087423
478
50485
G36
L
R
A
L
H
T
A
G
T
L
R
G
V
P
G
Zebra Danio
Brachydanio rerio
NP_956854
490
51982
W42
E
S
P
R
T
A
G
W
S
R
S
A
A
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624025
598
64649
T143
V
S
V
T
P
P
V
T
A
S
S
T
S
P
P
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
N57
Q
V
A
R
Q
Y
P
N
A
A
A
F
S
I
K
Sea Urchin
Strong. purpuratus
XP_001177721
482
51019
E36
L
P
N
K
L
N
N
E
E
L
D
R
M
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WQF7
637
68844
S65
I
T
R
M
D
D
S
S
P
K
P
I
L
R
F
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
M39
P
E
H
T
I
I
G
M
P
A
L
S
P
T
M
Red Bread Mold
Neurospora crassa
P20285
458
48601
P33
R
W
Y
A
S
Y
P
P
H
T
V
V
K
M
P
Conservation
Percent
Protein Identity:
100
99.5
87
90.2
N.A.
85.2
34.4
N.A.
N.A.
72.1
58.8
58
N.A.
N.A.
36.4
37.2
47.3
Protein Similarity:
100
99.8
87.6
93.2
N.A.
91.4
49.6
N.A.
N.A.
82
73.4
73
N.A.
N.A.
51.6
56.7
63
P-Site Identity:
100
100
13.3
53.3
N.A.
53.3
20
N.A.
N.A.
13.3
13.3
6.6
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
100
100
40
73.3
N.A.
66.6
26.6
N.A.
N.A.
13.3
26.6
6.6
N.A.
N.A.
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
32.7
34.7
Protein Similarity:
N.A.
N.A.
N.A.
48.9
51.9
51.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
14
40
7
14
7
0
14
14
7
7
34
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% C
% Asp:
0
0
0
0
7
7
0
0
0
7
7
0
0
0
0
% D
% Glu:
7
7
0
0
0
0
0
7
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
7
% F
% Gly:
7
0
34
0
0
34
20
14
7
7
0
34
7
14
7
% G
% His:
0
0
7
0
7
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
7
0
0
7
7
7
0
0
0
0
0
7
7
7
0
% I
% Lys:
0
14
0
7
0
0
0
0
0
7
0
0
7
0
7
% K
% Leu:
20
0
0
14
20
0
0
0
7
14
14
7
7
7
7
% L
% Met:
0
0
0
7
0
0
0
7
0
0
0
0
7
7
7
% M
% Asn:
0
0
7
0
0
7
7
7
0
0
0
0
0
14
0
% N
% Pro:
7
7
14
0
14
7
14
27
14
0
7
0
7
14
27
% P
% Gln:
7
7
0
0
7
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
7
20
7
14
7
0
0
0
7
14
40
7
0
14
0
% R
% Ser:
0
20
0
0
14
7
7
20
7
20
20
14
14
14
0
% S
% Thr:
0
7
0
14
7
7
0
7
7
7
0
7
0
14
0
% T
% Val:
20
14
7
0
7
0
7
0
27
0
7
7
7
0
0
% V
% Trp:
0
7
0
0
0
0
27
14
0
0
0
0
0
0
34
% W
% Tyr:
0
0
14
0
0
14
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _